Simple exploration of 1122-10-7

1122-10-7 3,4-Dibromo-1H-pyrrole-2,5-dione 14279, apyrrolines compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1122-10-7,3,4-Dibromo-1H-pyrrole-2,5-dione,as a common compound, the synthetic route is as follows.

A methanol solution (20 mL) of sodium acetate (360 mg,4.39 mmol) and propanethiol (304 mg, 4.00 mmol) was dropwisedinto a methanol solution (16 mL) of 2,3-dibromomaleimide (2.04 g,8 mmol)over 1 h. On completion of addition, the solution was stirredat room temperature for another 3 h. After that, the solutionwas concentrated and the crude product was purified by columnchromatography (SiO2, petroleum ether/ethyl acetate = 3/1) to producethe yellow solid product (520 mg) with a yield of 52%.

1122-10-7 3,4-Dibromo-1H-pyrrole-2,5-dione 14279, apyrrolines compound, is more and more widely used in various.

Reference£º
Article; Long, Shiyu; Tang, Qingquan; Wu, Ying; Wang, Luoxin; Zhang, Ke; Chen, Yongming; Reactive and functional polymers; vol. 80; 1; (2014); p. 15 – 20;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem