1334177-86-4, 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oic acid is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EDCI.HCI (0.13 g, 0.66 mmol, 1.1 eq.) was added to a cloudy solution of compound 21(0.61 g, 0.6 mmol, 1.0 eq.) and Mal-dPEG8-OH (0.393 g, 0.66 mmol, 1.1 eq.) in CHCI3(25 mL). The clear solution was stirred at room temperature for 1 .5h., diluted with CHCI3(100 mL) washed with brine (2 x 100 mL), dried (Mg504) and evaporated under reducedpressure to give a yellow foam. Purification by flash column chromatography [CHCI3/MeOH0% to 6% in 1% increments gave the product as a white foam (0.786 g, 82%). AnalyticalData: RT 1.44 mm; MS (ES) m/z (relative intensity) 1586 ([M + H],40), 1609 ([M + Na],100)
1334177-86-4, The synthetic route of 1334177-86-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ADC THERAPEUTICS SA; MEDIMMUNE LIMITED; VAN BERKEL, Patricius Hendrikus Cornelis; HOWARD, Philip Wilson; DUNNY, Elizabeth; HUTCHINSON, Ian; MASTERSON, Luke; (73 pag.)WO2017/137556; (2017); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem