1122-10-7, 3,4-Dibromo-1H-pyrrole-2,5-dione is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred solution of 2,3-dibromomaleimide (510 mg, 2.0 mmol) in CH2Cl2 (20 mL) Et3N(558 mL, 4.0 mmol) and n-hexyl-mercaptan (600 ml, 4.2 mmol) wereadded under an argon atmosphere and stirred for 3 h at roomtemperature. The reaction mixture was evaporated, and the crudeproduct was purified by flash chromatography (hexanes:ethyl acetate 9:1) to give compound 6a (526 mg, 80%) as a yellow powder.1H NMR (400 MHz, CDCl3): d 7.88 (s, 1H), 3.28 (t, J 7.4 Hz, 4H,2 x -SCH2), 1.70e1.59 (m, 4H, CH2), 1.47e1.37 (m, 4H), 1.35e1.24 (m,8H), 0.89 (t, J 6.7 Hz, 6H, 2x CH3). 13C NMR (101 MHz, CDCl3):d 166.6 (2C); 136.8 (CC); 31.9, 31.4, 30.6, 28.3 (8C, 8x CH2); 22.6(2C, 2 x CH2S); 14.1 (2C, 2x CH3). MS (ESI): m/z calculated forC16H27NO2S2 Na [M Na]: 352.138. Found: 352.201.
1122-10-7, 1122-10-7 3,4-Dibromo-1H-pyrrole-2,5-dione 14279, apyrrolines compound, is more and more widely used in various.
Reference£º
Article; Sz?cs, Zsolt; Kelemen, Viktor; Le Thai, Son; Csavas, Magdolna; R?th, Erzsebet; Batta, Gyula; Stevaert, Annelies; Vanderlinden, Evelien; Naesens, Lieve; Herczegh, Pal; Borbas, Aniko; European Journal of Medicinal Chemistry; vol. 157; (2018); p. 1017 – 1030;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem