With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6913-92-4,1-Benzyl-3-pyrroline,as a common compound, the synthetic route is as follows.
6913-92-4, Step 1 : To an ice-cooled solution of 26a (4.77g, 30mmol), 98% H2SO4 (1.95mL), H2O (4.5mL) and acetone (3OmL) was added 85% mCPBA (7.9 Ig, 39mmol) with stirring. The mixture was allowed to react for 48hrs at r.t. Acetone was evaporated and the mixture was neutralized with IN aq. NaOH and extracted with toluene. The organic phase was dried over anhy. MgSO4 and evaporated. The residue was purified by column chromatography (EArPE=I :4) to provide 26b (2.Og, 38%).
The synthetic route of 6913-92-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; XCOVERY, INC.; WO2008/33562; (2008); A2;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem