6913-92-4, 1-Benzyl-3-pyrroline is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
6913-92-4, a 5-benzyl-3-(tetrahydropyran-2-yloxymethyl)-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole To a solution of 1-benzyl-2,5-dihydro-1H-pyrrole (13.5 g, 84.8 mmol) in benzene (150 mL) was added 2-(2-nitroethoxy)tetrahydropyran (37 g, 211.2 mmol) and triethylamine (5.4 mL, 38.4 mmol). The solution was heated to reflux and phenyl isocyanate (37.8 mL, 347.8 mmol) was slowly added over 2 hours. After the addition was complete, the mixture was refluxed overnight and the resulting precipitate removed by filtration. The filtrate was concentrated in vacuo and the residue purified by column chromatography eluding with ethyl acetate:hexanes (1:4), to obtain 19.5 g the title compound. 1H NMR (200 MHz, CDCl3) delta 7.38-7.18 (m, 5H), 5.10-4.98 (m, 1H), 4.68-4.58 (bs, 1H), 4.50-4.18 (m, 2H), 3.86-3.42 (m, 5H), 3.25-3.05 (m, 2H), 2.44-2.24 (rA, 2H), 1.82-1.38 (m, 6H).
6913-92-4 1-Benzyl-3-pyrroline 561506, apyrrolines compound, is more and more widely used in various fields.
Reference£º
Patent; Ellsworth, Edmund Lee; Kerschen, James Alan; Powell, Sharon Anne; Sanchez, Joseph Peter; Showalter, Howard Daniel Hollis; Stier, Michael Andrew; Tran, Tuan Phong; US2003/114666; (2003); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem