69778-83-2,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.69778-83-2,4-Methoxy-1H-pyrrol-2(5H)-one,as a common compound, the synthetic route is as follows.
The 4-chloro-3-methoxy-2-E-butenoic acid, methyl ester thus obtained (84.42 g) was stirred with 210 ml of 28% aqueous ammonia solution under a reflux condenser at 80 C. for 2 hours. The mixture was then cooled to room temperature and extracted with methylene chloride. The extract was dried over sodium sulfate, filtered and solvent removed from the filtrate under reduced pressure. The residue was triturated with diethyl ether, giving 40, 6 g of 4-methoxy-3-pyrrolin-2-one, m.p. 132 C.
As the paragraph descriping shows that 69778-83-2 is playing an increasingly important role.
Reference£º
Patent; Researche Syntex France, S.A.; US4997846; (1991); A;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem