1122-10-7, 3,4-Dibromo-1H-pyrrole-2,5-dione is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of maleimide (2.0 g, 20.6 minol) in CHCI3 (20 mL) was added a solution of Br2(1.1 mL, 21.33 minol) in CHCI3 (15 mL). The mixture was heated to reflux for 2 h and thencooled to rt. The precipitate formed was collected by Buchner filtration (Whatman number5 paper) and washed with cold CHCI3 (2 x 50 mL) to afford the crude dibromo-maleimide asa pale yellow powder that was used without further purification. Crude dibromo-maleimidewas dissolved in anhydrous THF (50 mL) and cooled to 0 C. A solution of anhydrous NEt3(2.9 mL) in anhydrous THF (10 mL) was then added over 5 mins and the resulting pale pinksuspension stirred at 0 C for 2 h. Without warming, the suspension was filtered and thefiltrate concentrated in vacuo to afford the title compound 24 (2.30 g, 63%) as a light yellow solid. 1H NMR (400 MHz, CDCI3) oe 6.89 (1H, s, 5-H), 7.68 (1H, br s, 2-H); 13C NMR (100 MHz, CDCI3) oe 132.2, 132.8, 164.8, 167.8. The 1H and 13C NMR data obtained was in agreement with that reported from literature.20
1122-10-7, 1122-10-7 3,4-Dibromo-1H-pyrrole-2,5-dione 14279, apyrrolines compound, is more and more widely used in various fields.
Reference£º
Patent; SAMMUT, Ivan Andrew; HARRISON, Joanne Clare; HEWITT, Russell James; READ, Morgayn Iona; STANLEY, Nathan John; WOODS, Laura Molly; KUEH, Jui Thiang Brian; JAY-SMITH, Morgan; SMITH, Robin Andrew James; GILES, Gregory; LARSEN, Lesley; RENNISON, David; BRIMBLE, Margaret Anne; LARSEN, David Samuel; (209 pag.)WO2017/95237; (2017); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem