With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.17057-04-4,4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-benzoicacid,as a common compound, the synthetic route is as follows.
A mixture of 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)benzoic acid (30mg, 0.128mmol) and thionyl chloride (10mL) was refluxed overnight at 80C. Unreacted thionyl chloride was evaporated to yield the residual product N-[4-(chlorocarbonyl) phenyl] maleimide (4) which was used directly.
17057-04-4, 17057-04-4 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-benzoicacid 86925, apyrrolines compound, is more and more widely used in various fields.
Reference£º
Article; Shu, Hai; Wu, Xiaolei; Zhou, Baojing; Han, Yingbin; Jin, Mingjie; Zhu, Jing; Bao, Xiaofeng; Dyes and Pigments; vol. 136; (2017); p. 535 – 542;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem