119020-01-8, (S)-1-Boc-2-(Aminomethyl)pyrrolidine is a pyrrolidine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
STEP 1: (S)-2-[(2,2,2-Trifluoro-acetylamino)-methyl]-pyrrolidine-l-carboxylic acid tert-butyl ester (S)-l-Boc-2-(aminomethyl)pyrrolidine (10 g, 50 mmol) was dissolved in dry THF (200 mL) followed by the slow addition (within 5 min) of a solution of ethyl trifluoroacetate (9.75 g, 68 mmol) in THF (50 mL). Stirring at rt was continued for 2 h. The reaction mixture was evaporated to dryness and the residue dried at HV to give (S)-2-[(2,2,2- trifluoro-acetylamino)-methyl] -pyrrolidine- 1-carboxylic acid tert-butyl ester (14.8 g, quant, yield). LC-MS: tR = 0.93 min; [M+H]+ = 297.29.
119020-01-8, 119020-01-8 (S)-1-Boc-2-(Aminomethyl)pyrrolidine 1512533, apyrrolidine compound, is more and more widely used in various fields.
Reference£º
Patent; ACTELION PHARMACEUTICALS LTD; WO2008/139416; (2008); A1;,
Pyrrolidine – Wikipedia
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