31970-04-4, Benzyl 2,5-dihydro-1H-pyrrole-1-carboxylate is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Part A: Phenylmethyl (cis)-3,4-dihydroxy-1 -pyrrolidinecarboxylate. Phenylmethyl 2,5-dihydro-1/-/-pyrrole-1-carboxylate (commerically-available) (5.07 g, 25 mmol) was dissolved in a mixture of acetone (25 mL) and water (10 ml_). NMO (5.9 g, 50 mmol) was added followed by catalytic OsO4. The reaction was stirred for 19 hours and then quenched by the addition of an aqueous solution of Na2S2psi3. A standard workup followed by silica gel chromatography (3:1 Hexane:ethyl acetate to pure ethyl acetate to 9:1 DCM: MeOH) yielded phenylmethyl (cis)-3,4-dihydroxy-1-pyrrolidinecarboxylate (0.872 g, 15percent) as a clear oil. LCMS: (M+H)+: 237.9.
31970-04-4, The synthetic route of 31970-04-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SMITHKLINE BEECHAM CORPORATION; WO2009/61879; (2009); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem