55750-48-6, Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate is a pyrrolines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,55750-48-6
[3921] 186 mg (555 f.tmol) of 3-{2-[2-(2-aminoethoxyl)ethoxy ]ethoxy }propanoic acid trifluoroacetate were dissolvedin 2.6 ml of saturated sodiumhydrogencarbonate solutionand admixed at oo C. with 86 mg (555 f.tmol) ofN-methoxycarbonylmaleimide. The reaction mixture wasstirred at oo C. for 40 min and at RT for 1 h, then cooled againto oo C., adjusted to pH 3 with sulphuric acid and extracted 3xwith 25 ml of ethyl acetate. The combined organic phaseswere dried over magnesium sulphate and concentrated. 126mg (75% of theory) of the title compound were obtained.[3922] LC-MS (Method 1): R,=0.53 min; m/z=302(M+Ht.
The synthetic route of 55750-48-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SEATTLE GENETICS, INC.; LERCHEN, Hans-Georg; LINDEN, Lars; SHEIKH, Sherif El; WILLUDA, Joerg; KOPITZ, Charlotte C.; SCHUHMACHER, Joachim; GREVEN, Simone; MAHLERT, Christoph; STELTE-LUDWIG, Beatrix; GOLFIER, Sven; BEIER, Rudolf; HEISLER, Iring; HARRENGA, Axel; THIERAUCH, Karl-Heinz; BRUDER, Sandra; PETRUL, Heike; JOeRISSEN, Hannah; BORKOWSKI, Sandra; US2015/246136; (2015); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem