Derivation of elementary reaction about 1334177-86-4

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oic acid, you can also browse my other articles.

A balanced equation for a chemical reaction indicates what is reacting and what is produced, but it reveals nothing about how the reaction actually takes place. The reaction mechanism is the process, or pathway, by which a reaction occurs.1334177-86-4, name is 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oic acid. An updated downstream synthesis route of 1334177-86-4 as follows., 1334177-86-4

(C) (115,1 laS) -4-((2R, 5R) -3 7-(2, 5-dioxo-2 , 5-dihydro- 1H-pyrrol- 1-yI)-5-isopropyl-2-methyl- 4,7, 35-trioxo- 10, 13, 16, 19,22,25,28,3 1-octaoxa-3, 6, 34-triazaheptatriacontanamido)benzyl 11- hydroxy-8-((5-(((1 15, 1 laS)- 1 1-hydroxy- 1 0-(((4-((1OR, 13R)- lO-isopropyl- 13-met hyl-8, 11- dioxo-2, 5-dioxa-9, 12-diazatetradecanamido) benzyl) oxy)carbonyl)- 7-methoxy-2-methyl-5- oxo-5, 10, 11, 1 la-tetrahydro- 1H-pyrrolo[2, 1-c][1, 4]benzodiazepin-8-yI) oxy)pentyl) oxy) -7- methoxy-2-methyl-5-oxo- 11,1 la-dihydro- 1H-pyrrolo[2, 1-c][1, 4]benzodiaze pine- 10(5H)- carboxylate (106)N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (28 mg, 0.146 mmol, 1 eq) was added to a solution of 105 (203 mg, 0.146 mmol) and maleimide-PEG8 acid (87 mg, 0.146 mmol) in chloroform (5 mL). The reaction was stirred for 1.5 h then diluted with chloroform (50 mL), washed with water (50 mL), brine (30 mL), dried over magnesium sulphate, filtered and evaporated. Flash chromatography [gradient elution 100% DCM to 90% DCM/i0% methanol] gave 106 as a pale yellow solid (205 mg, 72%). LC/MS: RT 5.75 mm; MS (ES+) m/z (relative intensity) 982.90 (100), 1963.70 (5).

A chemical reaction often occurs in steps, although it may not always be obvious to an observer. Thank you very much for taking the time to read this article. If you are also interested in other aspects of 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oic acid, you can also browse my other articles.

Reference£º
Patent; CANCER RESEARCH TECHNOLOGY LIMITED; VAN BERKEL, Patricius Henrikus Cornelis; HOWARD, Philip Wilson; WILLIAMS, David G; WO2015/159076; (2015); A1;,
Pyrroline – Wikipedia
1-Pyrroline | C4H7N – PubChem