A new application about 73286-71-2

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In an article, published in an article,authors is Beng, Timothy K., once mentioned the application of 73286-71-2, Name is N-Boc-2-pyrroline,molecular formula is C9H15NO2, is a conventional compound. this article was the specific content is as follows. 73286-71-2

Regiocontrolled synthesis of (hetero)aryl and alkenyl dehydropyrrolidines, dehydropiperidines and azepenes by Ru-catalyzed, heteroatom-directed alpha-C-H activation/cross-coupling of cyclic enamides with boronic acids

The synthesis of alpha-aryl and alkenyl pyrrolidine-, piperidine-, and azepane derivatives, through the intermediacy of cyclic enamides is described. The desired outcome is achieved through ruthenium-catalyzed, site-selective sp2 C-H activation/cross-coupling with aryl and alkenyl boronic acids. The regioselectivity (alpha-sp2vs. alpha-sp3vs. beta-sp2 C-H functionalization) is governed by the rate differences between sp2 and sp3 C-H activation and the necessity for chelation between the ruthenium metal and the carbonyl directing group.

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Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem