In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Computed Properties of C12H12N2O4, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 28537-70-4, name is 1,1′-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione). In an article£¬Which mentioned a new discovery about 28537-70-4
Formation of a beta-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA
The beta-barrel assembly machine (Bam) complex in Gram-negative bacteria and its counterparts in mitochondria and chloroplasts fold and insert outer membrane beta-barrel proteins. BamA, an essential component of the complex, is itself a beta-barrel and is proposed to play a central role in assembling other barrel substrates. Here, we map the path of substrate insertion by the Bam complex using site-specific crosslinking to understand the molecular mechanisms that control beta-barrel folding and release. We find that the C-terminal strand of the substrate is stably held by BamA and that the N-terminal strands of the substrate are assembled inside the BamA beta-barrel. Importantly, we identify contacts between the assembling beta-sheet and the BamA interior surface that determine the rate of substrate folding. Our results support a model in which the interior wall of BamA acts as a chaperone to catalyze beta-barrel assembly.
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Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem