In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 1585-90-6, name is 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione, introducing its new discovery. name: 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione
Rhodium(III)-Catalyzed C-H Alkenylation: Access to Maleimide-Decorated Tryptophan and Tryptophan-Containing Peptides
Maleimide is widely applied in many fields, especially in antibody-drug conjugations and peptide drugs. Herein, we develop a strategy for the C-H alkenylation of tryptophan and tryptophan-containing peptides, providing a synthetic route of decorating maleimide on peptides. The method has a high tolerance of functional groups and protecting groups. Furthermore, this method was applied to prepare peptide conjugation with molecules such as drugs and fluorescence probes. Moreover, macrocyclic peptides were obtained via this reaction.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 1585-90-6, and how the biochemistry of the body works.name: 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione
Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem