One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C11H9NO3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1081-17-0, Name is 1-(4-Methoxyphenyl)-1H-pyrrole-2,5-dione, molecular formula is C11H9NO3
The effects of protopine on physiological characteristics of isolated guinea pig atrium
AIM: To study the effects of protopine(Pro) on physiological characteristics and action machines in isolated guinea pig atria. METHODS: We measured the spontaneous beat, contractility and functional refractory period and observed the effects of Pro on positive staircase phenomenon and post- rest potentiation by using isolated guinea pig atria. RESULTS: Pro obviously inhibited the spontaneous beat and contractive force, prolonged the functional refractory period (FRP) of isolated guinea pig atria. Pro could abolish the positive chronotropic effect of CaCl2. Pro markedly depressed the positive stairease phenomenon induced by increasing the frequency of the electrical pulse and decreased the post-rest potentiation of myocardial contractility in left atria. CONCLUSION: The results suggest that Pro induce inhibitory effects on the spontaneous beat, contractility and prolong the FRP in the atria. The mechanism by which the Pro induce the negative chronotropic and inotropic effects may relate to the inhibition of transmembrane flux of calcium.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C11H9NO3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 1081-17-0, in my other articles.
Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem