Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. HPLC of Formula: C4HBr2NO2. Introducing a new discovery about 1122-10-7, Name is 3,4-Dibromo-1H-pyrrole-2,5-dione
Synthesis and cytotoxicity of novel 3-amino-4-indolylmaleimide derivatives
In an attempt to develop potent and selective antitumor agents, a series of novel 3-amino-4- indolylmaleimides were designed and synthesized. The reaction showed high regioselectivity. The structure of compound 7a was determined by an X-ray single crystal diffraction method. The cytotoxicities of the title compounds were evaluated against HeLa, SMMC 7721 and HL 60 cancer cell lines by a standard MTT assay in vitro. The pharmacological results showed that some of the title compounds displayed moderate or high cytotoxic activity against the tested cell lines. Compound 7d was the most promising compound against the tested cancer cell lines. Structure-activity relationships are discussed based on the experimental data obtained. A hydroxyethylamino group at the 3-position in the side chain of indolylmaleimide is associated with an increase in cytotoxicity. Copyright
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C4HBr2NO2, you can also check out more blogs about1122-10-7
Reference£º
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem