Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 3446-89-7, Name is 4-(Methylthio)benzaldehyde, molecular formula is C8H8OS, belongs to pyrrolines compound, is a common compound. In a patnet, author is JIE, MSFLK, once mentioned the new application about 3446-89-7, Product Details of 3446-89-7.
ULTRASOUND IN FATTY-ACID CHEMISTRY – SYNTHESIS OF A 1-PYRROLINE FATTY-ACID ESTER ISOMER FROM METHYL RICINOLEATE
A novel 1-pyrroline fatty acid ester isomer [viz. 8-(5-hexyl-1-pyrrolin-2-yl)octanoate] has been synthesized from methyl ricinoleate by two routes with an overall yield of 42 and 30%, respectively. Most of the reactions are carried out under concomitant ultrasonic irradiation (20 KHz, ca. 53 watts/cm(2)). Under such a reaction condition, the reaction time is considerably shortened, and product yields are high. Dehydrobromination under concomitant ultrasonic irradiation of methyl 9,10-dibromo-12-hydroxyoctadecanoate with KOH in EtOH furnishes methyl 12-hydroxy-9-octadecynoate (66%) within 15 min. Hydration of the latter under ultrasound with mercury(II)acetate in aqueous tetrahydrofuran yields exclusively methyl 12-hydroxy-9-oxo-octadecanoate (95%) in 30 min. The hydroxy group in the latter compound is transformed to the azido function via the mesylate, and treatment of the azido-oxo intermediate (methyl 12-azido-9-oxooctadecanoate) with Ph(3)P under ultrasonic irradiation furnishes the requisite 1-pyrroline fatty acid ester (77%). The same azido-oxo intermediate has also been obtained by the oxidation of methyl 12-azido-9-cis-octadecenoate using benzoquinone and a catalytic amount of Pd(II)chloride in aqueous tetrahydrofuran under concomitant ultrasonic irradiation (90 min) to give the product in 45% yield. The latter reaction does not take place even the reaction mixture.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem