Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 155899-66-4, Name is (3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol, molecular formula is C8H15NO3, belongs to pyrrolines compound, is a common compound. In a patnet, author is Kuznecovs, Jevgenijs, once mentioned the new application about 155899-66-4, Product Details of 155899-66-4.
Synthesis and study of new 5-substituted 1-acetyl-4-phenyl-3-pyrrolin-2-ones as potential antitumor agents
The treatment of 1-acetyl-5-bromo-4-phenyl-3-pyrrolin-2-one with appropriate silver salts in benzene promotes the substitution of bromine with chloride, fluoride, nitrite, nitrate, and thiocyanate groups. Biological testing of the newly synthesized compounds resulted in the discovery of moderate indoleamine 2,3-dioxygenase and matrix metalloproteinase inhibiting properties for NO2 and SCN derivatives in combination with low antitumor effect in vivo. However, testing of the NO2 derivative in mice with transplanted 4T1 mammary and CT-26 mouse colon carcinomas led to a considerable decrease in tumor volume and lung metastases without undesirable toxic effects evidencing potent tumor supressing properties.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem