Chemistry, like all the natural sciences, Formula: C16H35O2P, begins with the direct observation of nature¡ª in this case, of matter.83411-71-6, Name is Bis(2,4,4-trimethylpentyl)phosphinic acid, SMILES is O=P(CC(C)CC(C)(C)C)(CC(C)CC(C)(C)C)O, belongs to pyrrolines compound. In a document, author is Liu, Hui, introduce the new discover.
Enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines
The first enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines was realized using a chiral phosphoric acid as catalyst. Various novel (bridged) isoxazoline fused dihydrobenzofurans bearing two continuous quaternary stereocenters were achieved in moderate to good yields (up to 94%) with moderate to good enantioselectivities (up to 98% ee). The absolute configurations of two products were assigned by X-ray crystal structural analyses and a plausible reaction mechanism was proposed.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 83411-71-6. Formula: C16H35O2P.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem