Synthetic Route of 56-12-2, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 56-12-2, Name is 4-Aminobutyric acid, SMILES is O=C(O)CCCN, belongs to pyrrolines compound. In a article, author is Wang, Zikun, introduce new discover of the category.
Cu(II)-catalyzed cyclization of alpha-diazo-beta-oxoamides with amines leading to pyrrol-3(2H)-ones
A novel Cu(II)-catalyzed cyclization of alpha-diazo-beta-oxoamides with amines has been developed, constituting a straightforward method to construct pyrrol-3(2H)-one rings. The intramolecular hydrogen bonding effect in alpha-diazo-beta-oxoamides plays an essential role in this reaction. A plausible reaction mechanism involving divergent generation and subsequent [2 + 3] cyclization of ketene and alpha-diazoimine intermediates was proposed.
Synthetic Route of 56-12-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 56-12-2.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem