In an article, author is Foden, Callum S., once mentioned the application of 17924-92-4, Name: (S,E)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione, Name is (S,E)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione, molecular formula is C18H22O5, molecular weight is 318.3643, MDL number is MFCD00133085, category is pyrrolines. Now introduce a scientific discovery about this category.
Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water
Peptide biosynthesis is performed by ribosomes and several other classes of enzymes, but a simple chemical synthesis may have created the first peptides at the origins of life. alpha-Aminonitriles-prebiotic alpha-amino acid precursors-are generally produced by Strecker reactions. However, cysteine’s aminothiol is incompatible with nitriles. Consequently, cysteine nitrile is not stable, and cysteine has been proposed to be a product of evolution, not prebiotic chemistry. We now report a high-yielding, prebiotic synthesis of cysteine peptides. Our biomimetic pathway converts serine to cysteine by nitrile-activated dehydroalanine synthesis. We also demonstrate that N-acylcysteines catalyze peptide ligation, directly coupling kinetically stable-but energy-rich-alpha-amidonitriles to proteinogenic amines. This rare example of selective and efficient organocatalysis in water implicates cysteine as both catalyst and precursor in prebiotic peptide synthesis.
If you are interested in 17924-92-4, you can contact me at any time and look forward to more communication. Name: (S,E)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem