Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Mase, N, once mentioned the application of 494-19-9, Name is Iminodibenzyl, molecular formula is C14H13N, molecular weight is 195.26, MDL number is MFCD00005070, category is pyrrolines. Now introduce a scientific discovery about this category, Application In Synthesis of Iminodibenzyl.
First synthesis of (R)-(-)-5-hydroxy-3-methyl-3-pyrrolin-2-one (jatropham) by lipase-catalyzed kinetic resolution
Jatropham, (R)-(-)-5-hydroxy-3-methyl-3-pyrrolin-2-one, is synthesized in three steps from citraconic anhydride. Highly regioselective reduction of citraconimide gives racemic jatropham in high yield. Kinetic resolution of racemic jatropham using lipase is also described. (C) 1999 Elsevier Science Ltd. All rights reserved.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem