Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter.525-76-8, Name is 2-Methyl-4H-benzo[d][1,3]oxazin-4-one, SMILES is O=C1C2=CC=CC=C2N=C(C)O1, belongs to pyrrolines compound. In a document, author is Palacios, Francisco, introduce the new discover, Quality Control of 2-Methyl-4H-benzo[d][1,3]oxazin-4-one.
Selective Synthesis of Substituted Pyrrole-2-phosphine Oxides and -phosphonates from 2H-Azirines and Enolates from Acetyl Acetates and Malonates
A simple and efficient selective synthesis of 1H-pyrrole-2-phosphine oxides 3 and -phosphonates 7 by addition of enolates derived from acetyl acetates to 2H-azirinylphosphine oxide 1 and -phosphonate 6 is reported. Nucleophilic addition of enolates derived from diethyl malonate to 2H-azirines 1 and 6 led to the formation of functionalized 2-hydroxy-1H-pyrrole-5-phosphine oxide 9 and -phosphonate 10, while vinylogous alpha-aminoalkylphosphine oxides 14 and -phosphonate 15 may be obtained from azirines and the enolate derived from diethyl 2-phenylmalonate. Ring closure of vinylogous derivatives 14 and 15 in the presence of base led to the formation of 1,5-dihydro-3-pyrrolin-2-ones containing a phosphine oxide 17 or a phosphonate group 18.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 525-76-8 is helpful to your research. Quality Control of 2-Methyl-4H-benzo[d][1,3]oxazin-4-one.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem