Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 10191-41-0, Name is DL-alpha-Tocopherol, SMILES is CC1=C2C(OC(CCCC(CCCC(CCCC(C)C)C)C)(C)CC2)=C(C(C)=C1O)C, belongs to pyrrolines compound. In a document, author is Dayam, Raveendra, introduce the new discover, Recommanded Product: 10191-41-0.
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase
The beta-diketoacid class of HIV-1 integrase (IN) inhibitors represent the first potent class of compounds specific for the strand transfer catalytic activity of the viral enzyme. Previously, utilizing a beta-diketoacid pharmacophore as a search query, we identified a substituted 2-pyrrolinone with modest IN inhibitory activity from a database of small-molecules [Dayam, R.; Sanchez, T.; Neamati, N. J. Med. Chem. 2005, 48, 8009]. In efforts to optimize this class of IN inhibitors, we carried out a structure-activity relationship analysis around the 2-pyrrolinone core. Here, we present a new class of 2-pyrrolinone IN inhibitors. (C) 2007 Elsevier Ltd. All rights reserved.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 10191-41-0 is helpful to your research. Recommanded Product: 10191-41-0.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem