New Advances in Chemical Research, May 2021.Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 7423-55-4, Name is 3-Maleimidopropionic acid, molecular formula is C7H7NO4, belongs to pyrrolines compound, is a common compound. In a patnet, author is Huang, Fei, once mentioned the new application about 7423-55-4, SDS of cas: 7423-55-4.
Copper-mediated intramolecular oxidative C-H/N-H cross-coupling of alpha-alkenoyl ketene N,S-acetals to synthesize pyrrolone derivatives
CuCl2 and CuBr2-mediated intramolecular oxidative C-H/N-H cross-coupling/halogenation of beta-thioalkyl-substituted alpha-alkenoyl ketene N,S-acetals occurred efficiently, affording 4-halo-5-thioalkyl-3-pyrrolones. Tunable C-S and C-halo bond transformations of the resultant pyrrolone derivatives led to highly functionalized N-heterocyclic compounds.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. In my other articles, you can also check out more blogs about 7423-55-4. SDS of cas: 7423-55-4.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem