New Advances in Chemical Research, May 2021.Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 1240948-77-9, Name is 5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile, molecular formula is C11H7FN2, belongs to pyrrolines compound, is a common compound. In a patnet, author is Ruan, Shixiang, once mentioned the new application about 1240948-77-9, Recommanded Product: 1240948-77-9.
Facile dehydration of primary amides to nitriles catalyzed by lead salts: The anionic ligand matters
The synthesis of nitrile under mild conditions was achieved via dehydration of primary amide using lead salts as catalyst. The reaction processes were intensified by not only adding surfactant but also continuously removing the only by-product, water from the system. Both aliphatic and aromatic nitriles can be prepared in this manner with moderate to excellent yields. The reaction mechanisms were obtained with high-level quantum chemical calculations, and the crucial role the anionic ligand plays in the transformations were revealed.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms. 1240948-77-9, you can contact me at any time and look forward to more communication. Recommanded Product: 1240948-77-9.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem