New Advances in Chemical Research in 2021. Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage , causing turnover rates to depend strongly on interfacial structure. 7423-55-4, Name is 3-Maleimidopropionic acid, molecular formula is , belongs to pyrrolines compound. In a document, author is West, RR, SDS of cas: 7423-55-4.
ZG-1494 alpha, a novel platelet-activating factor acetyltransferase inhibitor from Penicilium rubrum, isolation, structure elucidation and biological activity
A novel inhibitor of platelet-activating factor (PAF) acetyltransferase, an essential enzyme in the remodeling pathway of platelet-activating factor synthesis, was identified by a high throughput screen of natural product extracts of microbial origin. The compound, ZG-1494 alpha, was isolated from an ethyl acetate extract of a culture broth of Penicillium rubrum through bioassay guided fractionation. The structure of ZG-1494 alpha was determined by spectroscopic methods. A key feature of the structure, which is relatively rare among natural products, is the 5-hydroxy-3-pyrrolin-2-one moiety. A C-13-C-13 INADEQUATE was utilized to unambiguously determine the regiochemistry of this molecule.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. In my other articles, you can also check out more blogs about 7423-55-4. SDS of cas: 7423-55-4.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem