New Advances in Chemical Research, May 2021.Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 129946-88-9, Name is 5-(Trifluoromethyl)-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate, molecular formula is C14H8F6O3S2, belongs to pyrrolines compound, is a common compound. In a patnet, author is Seino, H, once mentioned the new application about 129946-88-9, Safety of 5-(Trifluoromethyl)-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate.
Synthesis and structure determinations of complexes containing a five-membered lactam structure based on organohydrazido(2-) ligands
Acid-catalyzed reactions of the hydrazido(2-) complexes cis,mer-[WX(2)(NNH2)(PMe(2)Ph)(3)] (X=Cl, Br) with phthalaldehyde gave the (phthalimidin-2-yl)imido complexes cis,mer-[WX(2)(NNCH2C6H4CO)(PMe(2)Ph)(3)], via the condensation of the terminal NH2 group with one of the formyl groups and the following cyclization to form a phthalimidine ring. Crystal structure of the chloro complex 3a was unambiguously determined by X-ray analysis. Reaction of 3a with HBr liberated the (phthalimidin-2-yl)imido ligand as 2-aminophthalimidine in moderate yield, while treatment of 3a with KOH in THF selectively cleaved the N-N bond to give phthalimidine. A similar condensation of the hydrazido(2-) complex trans-[WF(NNH2)(dppe)(2)](+) (8a(+); dppe=Ph(2)PCH(2)CH(2)PPh(2)) with phthalaldehyde resulted in the formation of the diazoalkane complex trans-[WF(NN=CHC6H4CHO)(dppe)(2)](+). However, further treatment of the latter complex with AlCl3 afforded the corresponding (phthalimidin-2-yl)imido complex trans-[WF(NNCH2C6H4CO)(dppe)(2)](+). When 8a(+) and its molybdenum analogue were reacted with 2,5-dimethoxy-2,5-dihydrofuran in the presence of a catalytic amount of acid, trans-[M(NNCH=CHCH2CO)(dppe)(2)](+) (11(+); M=Mo, W) was formed as the kinetic product, which gradually isomerized to the thermodynamically more stable compound trans-[MF(NNCH2CH=CHCO)(dppe)(2)](+) (12(+)). Both 11(+) and 12(+) (M=W) were crystallographically characterized, and the mechanism for the isomerization of 11(+) to 12(+) was proposed based on the results of the H-1 NMR measurements.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 129946-88-9. Safety of 5-(Trifluoromethyl)-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem