New Advances in Chemical Research, May 2021.Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 57-71-6, Name is Diacetyl Monoxime, molecular formula is C4H7NO2, belongs to pyrrolines compound, is a common compound. In a patnet, author is Huo, Hao-Hua, once mentioned the new application about 57-71-6, Recommanded Product: 57-71-6.
A Formal Enantioselective Total Synthesis of FR901483
A formal enantioselective total synthesis of the potent immunosuppressant FR901483 (1) has been accomplished. Our approach features the use of chiron 6 as the starting material, the application of the one-pot amide reductive bisalkylation method to construct the chiral aza-quaternary center (dr = 9:1), regio- and diastereoselective intramolecular aldol reaction to build the bridged ring, and ring closing metathesis to form the 3-pyrrolin-2-one ring.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. In my other articles, you can also check out more blogs about 57-71-6. Recommanded Product: 57-71-6.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem