Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment. 766-36-9, Name is 3-Ethyl-4-methyl-2,5-dihydro-1H-pyrrol-2-one, molecular formula is , belongs to pyrrolines compound. In a document, author is Kuznecovs, Jevgenijs, Formula: https://www.ambeed.com/products/766-36-9.html.
Synthesis and study of new 5-substituted 1-acetyl-4-phenyl-3-pyrrolin-2-ones as potential antitumor agents
The treatment of 1-acetyl-5-bromo-4-phenyl-3-pyrrolin-2-one with appropriate silver salts in benzene promotes the substitution of bromine with chloride, fluoride, nitrite, nitrate, and thiocyanate groups. Biological testing of the newly synthesized compounds resulted in the discovery of moderate indoleamine 2,3-dioxygenase and matrix metalloproteinase inhibiting properties for NO2 and SCN derivatives in combination with low antitumor effect in vivo. However, testing of the NO2 derivative in mice with transplanted 4T1 mammary and CT-26 mouse colon carcinomas led to a considerable decrease in tumor volume and lung metastases without undesirable toxic effects evidencing potent tumor supressing properties.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 766-36-9. The above is the message from the blog manager. Formula: https://www.ambeed.com/products/766-36-9.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem