In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. 229625-50-7, Name is Di-tert-butyl chloromethyl phosphate, molecular formula is C9H20ClO4P. In an article, author is Qiu, Xiao-Feng,once mentioned of 229625-50-7, Quality Control of Di-tert-butyl chloromethyl phosphate.
Late-Stage Transformation of Carboxylic Acids to N-Trifluoroethylimides with Trifluoromethyl Diazomethane
We report the first systematic evaluation of the reaction of trifluoromethyl diazomethane (2,2,2-trifluorodiazoethane, CF3CHN2) with drug-like molecules. We found our previous copper-catalyzed transformation of carboxylic acids to the corresponding N-trifluoroethylimides with CF3CHN2 and acetonitrile is well-suited for the latestage modification of drug and drug-like acids. A procedure that enables the use of solid nitriles and nitriles with high boiling points as viable substrates is also disclosed.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem