Chemical engineers work across a number of sectors, processes differ within each of these areas, but chemistry and chemical engineering roles are found throughout, and are directly involved in the process of chemical products and materials. 5306-85-4, Name is (3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan, molecular formula is , belongs to pyrrolines compound. In a document, author is Ramireddy, Naresh, Reference of 5306-85-4.
Base-catalyzed reaction between isatins and N-Boc-3-pyrrolin-2-one
The base-catalyzed reaction between isatins and N-Boc-3-pyrrolin-2-one yields Morita-Baylis-Hillman (MBH) adducts instead of the expected aldol products in good to high yields (up to 97%). Various organic and inorganic bases are efficient catalysts for this reaction. Our study excluded the Morita-Baylis-Hillman mechanism for the formation of the MBH-type products. The MBH products are most likely formed as a result of the subsequent isomerization of the original aldol products between isatins and N-Boc-3-pyrrolin-2-one. (C) 2013 Elsevier Ltd. All rights reserved.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 5306-85-4 is helpful to your research. Reference of 5306-85-4.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem