The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, spectroscopic, and theoretical assessments of solvent structures and their interactions with reaction intermediates. 5306-85-4, Name is (3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan, molecular formula is C8H14O4, belongs to pyrrolines compound, is a common compound. In a patnet, author is Snider, BB, once mentioned the new application about 5306-85-4, Application of 5306-85-4.
A novel biomimetic route to the 3-acyl-5-hydroxy-3-pyrrolin-2-one and 3-acyl-3,4-epoxy-5-hydroxypyrrolidin-2-one ring systems
Modified Moffat oxidation of alcohols 17, 22, and 25 afforded aldehydes that underwent intramolecular aldol reactions on treatment with a NaOH solution to yield 4-pyrrolin-2-ones 16, 23, and 26. Oxidation with DMDO at -40 degreesC provided 3-acyl-5-hydroxy-3-pyrrolin-2-ones 18, 24, and 27 with the ring system of oteromycin (3), UCS1025A (5), and related natural products. Further oxidation of 18 yielded 3-acyl-3,4-epoxy-5-hydroxy-pyrrolidin-2-one 19 with the ring system of fusarin C (1) and epolactaene (2). Dehydration of 18 afforded 20 with the talaroconvolutin A (4) ring system.
Application of 5306-85-4, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 5306-85-4.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem