Some examples of the diverse research done by chemistry experts include discovery of new medicines and vaccines, improving understanding of environmental issues, and development of new chemical products and materials. 17924-92-4, Name is (S,E)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione, molecular formula is C18H22O5, belongs to pyrrolines compound, is a common compound. In a patnet, author is Besbes, R, once mentioned the new application about 17924-92-4, Reference of 17924-92-4.
Improved synthesis and reaction of dimethyl a-(bromomethyl) fumarate with primary amines
Dimethyl alpha-(bromomethyl) fumarate (2) has been prepared in one pot by addition of bromine to dimethyl itaconate and dehydrobromination with triethylamine. The allylic bromide 2, reacts with primary amines via two successive allylic substitutions and followed by lactamization at a high temperature (above 150 degrees C) to give 4-methoxycarbonyl-1-N-alkyl-Delta(3)-pyrrolin-2-ones (7) in good yields.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem