With the volume and accessibility of scientific research increasing across the world, it has never been more important to continue building the reputation for quality and ethical publishing we’ve spent the past two centuries establishing.56-85-9, Name is H-Gln-OH, molecular formula is C5H10N2O3, belongs to pyrrolines compound, is a common compound. In a patnet, author is Coffin, Aaron R., once mentioned the new application about 56-85-9, Synthetic Route of 56-85-9.
Regiocontrolled synthesis of pyrrole-2-carboxaldehydes and 3-pyrrolin-2-ones from pyrrole Weinreb amides
A regiocontrolled synthesis of 3,4-disubstituted pyrrole-2carboxaldehydes was completed in two steps from acyclic starting materials. A Barton-Zard pyrrole synthesis between N-methoxy-N-methyl-2-isocyanoacetamide and R-nitroalkenes or,-nitroacetates provided N-methoxy-N-methyl pyrrole-2-carboxamides ( pyrrole Weinreb amides), which were converted into the corresponding pyrrole-2-carboxaldehydes by treatment with lithium aluminum hydride. A regioselective oxidation of the pyrrole-2-carboxaldehydes gave the corresponding 3,4-disubstituted 3-pyrrolin-2-ones.
Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.Read on for other articles about 56-85-9. Synthetic Route of 56-85-9.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem