Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 29968-78-3, Name is 4-Nitrophenylethylamine hydrochloride, molecular formula is C8H11ClN2O2, belongs to pyrrolines compound, is a common compound. In a patnet, author is da Silva, Fabio M., once mentioned the new application about 29968-78-3, Application In Synthesis of 4-Nitrophenylethylamine hydrochloride.
Regio- and stereoselective synthesis of polysubstituted 5-hydroxypyrrolidin-2-ones from 3-alkoxysuccinimides
The synthesis of 4-ethoxy-5-hydroxypyrrolidin-2-ones and 6-hydroxyhexahydro-4-H-furo[2,3-clpyrrol-4-ones – through the regio- and stereoselective reduction of the corresponding 3-alkoxysuccinimides – is described. The reaction used NaBH4 at low temperatures and short reaction times, providing products with yields of up to 77%. The stereoselectivity was highly influenced by both alkoxy and the N-moiety in the starting succinimide. (C) 2019 Elsevier Ltd. All rights reserved.
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Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem