In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. 525-76-8, Name is 2-Methyl-4H-benzo[d][1,3]oxazin-4-one, molecular formula is C9H7NO2. In an article, author is Groselj, Uros,once mentioned of 525-76-8, COA of Formula: https://www.ambeed.com/products/525-76-8.html.
Synthesis of Spiro-Delta(2)-Pyrrolin-4-One Pseudo Enantiomers via an Organocatalyzed Sulfa-Michael/Aldol Domino Sequence
Delta(2)-Pyrrolin-4-ones undergo organocatalyzed sulfa-Michael/aldol domino spirocyclizations with mercaptoacetaldehyde dimer. The products contain three contiguous stereocenters (ee up to 99%, dr up to 95:5, 25 examples) and can be transformed into analogues of natural products. With the use of a single catalyst, the absolute configuration of the products were determined by the configuration of the exocyclic double bond of the starting material. These results point at the possibility of a widespread use of unsaturated Delta(2)-pyrrolin-4-ones in various (organo)catalyzed (cascade) transformations for accessing libraries of 3D-rich pyrrolone-based (spiro)heterocycles.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 525-76-8 is helpful to your research. COA of Formula: https://www.ambeed.com/products/525-76-8.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem