The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, spectroscopic, and theoretical assessments of solvent structures and their interactions with reaction intermediates. 256-96-2, Name is 5H-Dibenzo[b,f]azepine, molecular formula is C14H11N, belongs to pyrrolines compound, is a common compound. In a patnet, author is Gheorghe, A, once mentioned the new application about 256-96-2, Product Details of 256-96-2.
Synthesis of functionalized pyrrolidin-2-ones and (S)-Vigabatrin from pyrrole
Starting from pyrrole, the novel 3,4-didehydropyrohomoglutamate 8 or (ent)-8 can be efficiently synthesized in up to 91% ee, which can be utilized as a versatile building block toward functionalized pyrrolidin-2-ones. Moreover, (ent)-8 can be readily converted to (S)-Vigabatrin, being an irreversible inhibitor for GABA-T, which is used as adjunctive therapy in patients that suffer from epilepsy.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 256-96-2, you can contact me at any time and look forward to more communication. Product Details of 256-96-2.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem