Recommanded Product: 112275-50-0, When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process. 112275-50-0, Name is tert-Butyl 1,4-diazepane-1-carboxylate, SMILES is O=C(N1CCNCCC1)OC(C)(C)C, belongs to pyrrolines compound. In a article, author is KOEHN, FE, introduce new discover of the category.
ANALOGS OF THE MARINE IMMUNOSUPPRESSANT MICROCOLIN-A – PREPARATION AND BIOLOGICAL-ACTIVITY
A series of analogs of the immunosuppressive lipopeptide microcolin A has been prepared and evaluated for in vitro activity in the human and murine two-way mixed lymphocyte reaction. The compounds tested were obtained by semisynthetic modification and chemical degradation of the natural product. The relative potencies of these analogs suggest that the hydroxyproline and 5-methyl-3-pyrrolin-2-one portion of the molecule are important for immunosuppressive activity and that other structural elements may play an ancillary role. Methanolysis of microcolin A also led to a novel immunosuppressive lactone analog.
Interested yet? This just the tip of the iceberg, You can reading other blog about 112275-50-0. Recommanded Product: 112275-50-0.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem