Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 494-19-9, Name is Iminodibenzyl, molecular formula is , belongs to pyrrolines compound. In a document, author is Wang, Zikun, Computed Properties of https://www.ambeed.com/products/494-19-9.html.
Cu(II)-catalyzed cyclization of alpha-diazo-beta-oxoamides with amines leading to pyrrol-3(2H)-ones
A novel Cu(II)-catalyzed cyclization of alpha-diazo-beta-oxoamides with amines has been developed, constituting a straightforward method to construct pyrrol-3(2H)-one rings. The intramolecular hydrogen bonding effect in alpha-diazo-beta-oxoamides plays an essential role in this reaction. A plausible reaction mechanism involving divergent generation and subsequent [2 + 3] cyclization of ketene and alpha-diazoimine intermediates was proposed.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules. In my other articles, you can also check out more blogs about 494-19-9. Computed Properties of https://www.ambeed.com/products/494-19-9.html.
Reference:
Pyrroline – Wikipedia,
,1-Pyrroline | C4H7N – PubChem