Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 58081-05-3, is researched, Molecular C4H6O3, about Single-step conversion of chiral carnitine and derivatives into (S)- and (R)-β-substituted γ-butyrolactones, the main research direction is butyrolactone preparation; carnitine cyclocondensation.Safety of (R)-4-Hydroxydihydrofuran-2(3H)-one.
An efficient 1-step conversion of chiral carnitine and its derivatives into stereoisomerically pure (S)- and (R)-β-substituted γ-butyrolactones by cyclocondensation is described. (S)- or (R)-carnitine and (R)-aminocarnitine give β-hydroxy-γ-butyrolactone and β-amino-γ-butyrolactone in 82 and 77% yield, resp., with retention. (R)-(acetylamino)carnitine gives (R)-β-acetylamino-γ-butyrolactone in 90% yield, while (R)-acetylcarnitine gives 2(5H)-furanone under the same reaction conditions in 77% yield via cyclization and subsequent elimination. (R)-N-benzyloxycarnitinamide gives a mixture of pyrrolidinone (11% yield) and furanoyl imidate (50% yield) derivatives
Here is a brief introduction to this compound(58081-05-3)Safety of (R)-4-Hydroxydihydrofuran-2(3H)-one, if you want to know about other compounds related to this compound(58081-05-3), you can read my other articles.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem