Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 34941-92-9, is researched, SMILESS is ClC1=CC(=NC=C1)F, Molecular C5H3ClFNJournal, Article, Journal of Organic Chemistry called Preparative-Scale Synthesis of Vedejs Chiral DMAP Catalysts, Author is Kinens, Artis; Balkaitis, Simonas; Suna, Edgars, the main research direction is scalable synthesis chiral Vedejs type DMAP catalyst; amination pyridine zinc amine complex; mechanistic study zinc facilitated nucleophilic aromatic substitution.COA of Formula: C5H3ClFN.
A scalable synthesis of chiral Vedejs-type DMAP catalysts is reported. The key step of the synthesis is amination of the enantiomerically pure 4-chloropyridine derivative using well-defined ZnCl2(amine)2 complexes. A series of Zn(II)-amine complexes have been synthesized to explore the scope of the ZnCl2-mediated amination of 4-halopyridines. Mechanistic studies support a Zn(II)-facilitated nucleophilic aromatic substitution as a plausible mechanism for the chlorine-to-amine exchange.
From this literature《Preparative-Scale Synthesis of Vedejs Chiral DMAP Catalysts》,we know some information about this compound(34941-92-9)COA of Formula: C5H3ClFN, but this is not all information, there are many literatures related to this compound(34941-92-9).
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem