In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called New synthesis method of 2,6-dichloro-3-fluoropyridine, published in 2014-08-26, which mentions a compound: 52208-50-1, mainly applied to dichloro fluoropyridine nitrification catalytic hydrogenation reduction diazotization, Formula: C5H2Cl2FN.
2, 6-Dichloro-3-nitropyridine was synthesized from 2, 6-dichloropyridine by nitrification reaction. Then 2,6-dichloro-3-aminopyridine was synthesized from 2,6-dichloro-3-nitropyridine by the catalytic hydrogenation reduction reaction. At last, 2,6-dichloro-3-fluoropyridine was synthesized from 2,6-dichloro-3-aminopyridine by the diazotization reaction. Overall yield of three steps reaction was 69.3%. The target compound was confirmed by MS and NMR. The factors such as nitric acid concentration, the type and amount of catalyst and the molar ratio of sodium nitrite were discussed in detail. This synthesis route has high yield, high selectivity, and better prospect of industrialization.
In some applications, this compound(52208-50-1)Formula: C5H2Cl2FN is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem