The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2,6-Dichloro-3-fluoropyridine(SMILESS: ClC1=NC(=CC=C1F)Cl,cas:52208-50-1) is researched.SDS of cas: 616-14-8. The article 《Synthesis of fluorinated pyridines by the Balz-Schiemann reaction. An alternative route to enoxacin, a new antibacterial pyridonecarboxylic acid》 in relation to this compound, is published in Journal of Heterocyclic Chemistry. Let’s take a look at the latest research on this compound (cas:52208-50-1).
Fluorination of the 2,6-disubstituted 3-aminopyridines I (R = SEt, pyrrolidino, 4-ethoxycarbonylpiperazino, 4-acetylpiperazino, R1 = NHAc; R = R1 = Cl) by the Balz-Schiemann reaction gave 3-pyridinediazonium tetrafluoroborates which were heated with or without a solvent to give the corresponding fluorinated pyridines, in good yields. 2-Substituted 6-acetylamino-3-fluoropyridines were converted by a known method into a series of 7-substituted 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids including enoxacin (II).
There is still a lot of research devoted to this compound(SMILES：ClC1=NC(=CC=C1F)Cl)Category: pyrrolines, and with the development of science, more effects of this compound(52208-50-1) can be discovered.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem