Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (R)-4-Hydroxydihydrofuran-2(3H)-one, is researched, Molecular C4H6O3, CAS is 58081-05-3, about Absolute stereochemistries of the aplysiatoxins and oscillatoxin A.COA of Formula: C4H6O3.
CD and proton NMR spectral studies of the aplysiatoxins and derivatives, degradation products of the toxins, and an X-ray crystallog. anal. of 19,21-dibromoaplysiatoxin show that the absolute configurations of the ten asym. carbons are 3S,4R,7S,9S,10S,11R,12S,15S,29R,30R. The 31-nor compound, oscillatoxin A, has the same absolute stereochem. at C(3), C(4), C(7), C(9), C(10), C(11), C(12), C(15), and C(29).
There is still a lot of research devoted to this compound(SMILES：O=C1OC[C@H](O)C1)COA of Formula: C4H6O3, and with the development of science, more effects of this compound(58081-05-3) can be discovered.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem