Chemistry Milestones Of 58081-05-3

Here is just a brief introduction to this compound(58081-05-3)Electric Literature of C4H6O3, more information about the compound((R)-4-Hydroxydihydrofuran-2(3H)-one) is in the article, you can click the link below.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Diastereoselective Synthesis of C2′-Fluorinated Nucleoside Analogues Using an Acyclic Approach, published in 2016-11-18, which mentions a compound: 58081-05-3, Name is (R)-4-Hydroxydihydrofuran-2(3H)-one, Molecular C4H6O3, Electric Literature of C4H6O3.

Nucleoside analogs bearing a fluorine in the C2′-position have been synthesized by SN2-like cyclizations of acyclic thioaminal precursors. This strategy provides access to two scaffolds, D-1′,2′-cis-thiofuranosides and D-1′,2′-trans-furanosides, which are difficult to generate using the standard approach for nucleoside synthesis. The addition of silylated nucleobases onto model C2-fluorinated dithioacetal substrates resulted in 1,2-syn diastereoselectivity, which is consistent with the C2-F and S-alkyl moiety being in close proximity. A new series of analogs bearing a C3′ all-carbon quaternary center along with a C2′-F atom have also been synthesized using this approach and are being investigated as potential antimetabolites.

Here is just a brief introduction to this compound(58081-05-3)Electric Literature of C4H6O3, more information about the compound((R)-4-Hydroxydihydrofuran-2(3H)-one) is in the article, you can click the link below.

Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem