Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Chloro-5-iodo-3-methylpyridine, is researched, Molecular C6H5ClIN, CAS is 59782-89-7, about Some 2,5- and 5,6-dihalonicotinic acids and their precursors. IV.Reference of 2-Chloro-5-iodo-3-methylpyridine.
The pyridinecarboxylic acids I (R = Cl, R1 = CO2H, R2 = Cl, iodo; R = Cl, R1 = Cl, iodo, R2 = CO2H) were prepared by oxidation of I (R = Cl, R1 = Me, R2 = Cl, iodo; R = Cl, R1 = Cl, iodo, R2 = Me; resp.), which were prepared by diazotization and substitution of I (R = Cl, R1 = Me, R2 = NH2; R = Cl, R1 = NH2, R2 = Me; resp.). I (R = R1 = Cl, R2 = CO2H) and NaI gave I (R = iodo, R1 = Cl, R2 = CO2H).
Compound(59782-89-7)Reference of 2-Chloro-5-iodo-3-methylpyridine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-Chloro-5-iodo-3-methylpyridine), if you are interested, you can check out my other related articles.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem