Fier, Patrick S.; Hartwig, John F. published the article 《Selective C-H Fluorination of Pyridines and Diazines Inspired by a Classic Amination Reaction》. Keywords: carbon hydrogen fluorination pyridine diazine inspired classic amination.They researched the compound: 4-Chloro-2-fluoropyridine( cas:34941-92-9 ).Reference of 4-Chloro-2-fluoropyridine. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:34941-92-9) here.
Fluorinated heterocycles are prevalent in pharmaceuticals, agrochems., and materials. However, reactions that incorporate fluorine into heteroarenes are limited in scope and can be hazardous. The authors present a broadly applicable and safe method for the site-selective fluorination of a single carbon-hydrogen bond in pyridines and diazines using com. available silver(II) fluoride. The reactions occur at ambient temperature within 1 h with exclusive selectivity for fluorination adjacent to nitrogen. The mild conditions allow access to fluorinated derivatives of medicinally important compounds, as well as a range of 2-substituted pyridines prepared by subsequent nucleophilic displacement of fluoride. Mechanistic studies demonstrate that the pathway of a classic pyridine amination can be adapted for selective fluorination of a broad range of nitrogen heterocycles.
There are many compounds similar to this compound(34941-92-9)Reference of 4-Chloro-2-fluoropyridine. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem