Electric Literature of C5H3ClFN. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 4-Chloro-2-fluoropyridine, is researched, Molecular C5H3ClFN, CAS is 34941-92-9, about C-O Cross-Coupling of Activated Aryl and Heteroaryl Halides with Aliphatic Alcohols. Author is Maligres, Peter E.; Li, Jing; Krska, Shane W.; Schreier, John D.; Raheem, Izzat T..
The authors describe a Pd/Josiphos catatyst system for alkoxylation of activated aryl and heteroaryl halides with primary, secondary, and select tertiary alcs. E.g., in presence of [Pd2(dba)3] and ligand CyPF-tBu (I), C-O cross-coupling of 4-chloro-2-methylquinoline and PhCH2CH2OH gave 99% aromatic ether 4-(2-phenylethoxy)-2-methylquinoline.
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Reference:
Pyrroline – Wikipedia,
1-Pyrroline | C4H7N – PubChem